In 2020, scientists published a breakthrough study in PNAS (“The aging skin microenvironment dictates stem cell behavior”) showing just how important the scalp environment is for healthy hair growth.
They discovered that even young, healthy hair follicles stopped growing when placed into aged skin, but aged follicles could regrow when supported by youthful, healthy skin. In other words, your scalp is like the soil and your hair follicles are the seeds—without fertile soil, even the best seeds can’t thrive. This research proves that caring for the scalp itself is essential to unlocking fuller, stronger hair.
As we age, external forces accelerate the thinning of our hair just as they do the wrinkling of our skin. Environmental stressors like pollution, UV exposure, smoking, and even daily stress trigger the buildup of free radicals—unstable molecules that damage DNA and proteins in the scalp. This process, known as oxidative stress, weakens the scalp environment and compromises its ability to support healthy hair growth. Protecting the scalp from these environmental aggressors is critical to maintaining strong, vibrant hair. That’s why KilgourMD serums are enriched with powerful antioxidants, helping defend your scalp against oxidative stress and preserving its ability to grow healthy hair.
Another hidden driver of scalp aging is a process called “inflammaging”—chronic, low-level inflammation that builds up over time. Dandruff, harsh hair care products, and other irritants can fuel this ongoing inflammation, further damaging scalp cells and accelerating hair thinning. By calming inflammation and restoring balance to the scalp, we can help slow down this age-related process and create the ideal environment for thicker, healthier hair to flourish. KilgourMD formulas are designed to actively soothe the scalp, reduce inflammation, and restore a healthy foundation for long-term hair growth.
The breakthrough ingredient that increased hair growth by 214% in clinical studies. This patented molecule contains two key molecules that work together to reactivate dormant stem cells in hair follicles, essentially "waking up" sleeping follicles that have gone quiet. By targeting the hair follicle stem cells (ORSc), Redensyl® triggers new hair growth at the cellular level. In studies, it performed 2x better than minoxidil at stimulating growth - without any of the side effects. The molecule also protects against follicle inflammation and provides nutrients essential for healthy hair production.
A scientifically advanced complex that reduces inflammation by 48% while increasing hair density by 79% in just 4 months. This powerful ingredient combines red clover extract rich in Biochanin A (a natural DHT blocker) with acetyl tetrapeptide-3, a biomimetic peptide that strengthens hair anchoring at the root. By addressing both inflammation and follicle miniaturization simultaneously, Capixyl® creates an optimal scalp environment where hair can thrive. Clinical studies show it outperforms minoxidil by 81% while being completely natural and side-effect free.
A bioengineered complex that improves follicle blood flow by 121% while reducing hair loss by 58%. This trio of active molecules (biotinyl tripeptide-1, apigenin, and oleanolic acid) works synergistically to prevent follicle aging and strengthen the hair bulb structure. Procapil® fights follicle aging by protecting against free radical damage while improving cellular metabolism. It also blocks DHT locally at the follicle without affecting hormone levels elsewhere, making it ideal for menopausal women seeking natural solutions.
Derived from organic pea sprouts, this ingredient extends your hair's anagen (growth) phase by up to 78%, meaning each strand grows significantly longer before naturally shedding. By reducing the telogen (resting) phase by 34%, it ensures more follicles stay actively producing hair at any given time. AnaGain™ works by reactivating specific genes (FGF7 and Noggin) that control hair growth cycles. Clinical studies show it increases hair density through direct stimulation of dermal papilla cells - the "command center" of each follicle responsible for hair production.
Revolutionary plant stem cell technology from basil hairy roots that reduces hair loss by 31% in just 2 months. This sustainable ingredient blocks 5α reductase II (the enzyme that creates DHT) while simultaneously stimulating dermal papilla cells to keep follicles in their growth phase longer. The patented "hairy root" extraction method preserves the full spectrum of bioactive compounds, including powerful antioxidants that protect follicles from environmental damage and premature aging. Studies confirm it successfully prevents hair loss while promoting fuller, denser hair growth.
By mitigating oxidative stress and promoting collagen gene expression, vitamin C combats photoaging and natural scalp aging. Clinical evidence supports its role in increasing dermal collagen, which is essential for maintaining healthy hair follicles. The vitamin C in our formula works synergistically with other antioxidants to protect follicles from free radical damage while supporting the structural integrity of the scalp tissue where follicles are anchored.
A well-established natural inhibitor of 5-α reductase—the enzyme that converts testosterone into DHT, the main driver of follicle miniaturization. Clinical reviews have shown that Saw Palmetto can reduce androgen receptor activity in the scalp by 50%, and it is linked to reduced hair shedding and increased hair thickness without systemic side effects. Its anti-inflammatory properties also support overall scalp health.
Rosemary extract has demonstrated strong anti-inflammatory and antioxidant effects, particularly beneficial for scalp health. A 2020 review highlighted that rosemary improves scalp circulation, soothes irritation, and may be as effective as Minoxidil in improving hair count in some contexts. Its use has been associated with reduced scalp itchiness, decreased dandruff, and improved follicular environment, particularly in individuals with inflammation-related hair thinning.
Contains ginsenosides, bioactive compounds known to stimulate hair follicles, promote cell proliferation, and reduce inflammation. A 2020 review outlined its use in herbal hair loss treatments, citing improved follicular strength, hair shaft thickness, and overall scalp health. Ginseng also supports microcirculatory flow in the scalp, enhancing nutrient delivery while calming inflammatory responses tied to thinning and flaking.
Rich in antioxidants and vitamin C, offering significant protective and regenerative benefits for the scalp. A 2020 clinical study evaluated a hair serum containing amla over 90 days. Results showed a notable increase in hair growth rate, density, and reduced hair fall. The serum was well tolerated, with no adverse events, and demonstrated strong support for healthier, more resilient hair. Amla's high antioxidant content helps counter oxidative stress at the follicular level, preserving hair integrity and supporting rejuvenation.
Contains phytosterols, zinc, and omega fatty acids that naturally inhibit 5-α reductase, the enzyme responsible for converting testosterone to DHT. A 2014 study demonstrated a 40% increase in hair count and 30% improvement in hair thickness after 24 weeks of use. The extract also provides essential minerals that support keratin production, while its anti-inflammatory properties help maintain optimal scalp pH and reduce oxidative stress linked to follicle miniaturization.
Penetrates hair follicles within 2 minutes of topical application, where it blocks DHT effects and stimulates cellular metabolism. This powerful ingredient extends the anagen (growth) phase by 37% and increases hair shaft elongation by 46%. It enhances ATP production in follicular cells, counteracts testosterone-induced follicle suppression, and improves barrier function. Unlike systemic caffeine intake, topical application delivers therapeutic doses directly to follicles without side effects.
A potent antioxidant and anti-inflammatory compound shown to support microcirculation and neutralize free radicals in scalp tissue. It helps protect follicular DNA from oxidative damage, which is especially relevant during menopause when antioxidant production declines. Pine Bark (notably as Pycnogenol®) has shown strong antioxidant effects in skin studies and is commonly used to reduce oxidative aging and inflammation—both of which are known contributors to follicle aging and hair loss.
Turmeric's active compound, curcumin, is a potent natural anti-inflammatory shown to inhibit 5-α reductase and suppress inflammatory cytokines. In hair loss contexts, it has been studied for its role in soothing scalp inflammation, balancing microbiota, and reducing oxidative stress. A 2020 systemic review emphasized turmeric's ability to address hormonal and inflammatory triggers of alopecia while enhancing follicle resilience in stressed scalps.
Contained within The Prevention, piroctone, bisabolol, panthenol, and zinc combine to soothe the scalp and reduce harmful 'inflammaging'.
The combination of Redensyl®, Capixyl® & Procapil® (all found within the revolutionary KilgourMD system) was demonstrated to be superior to maximum strength 5% minoxidil across all outcome measures (including a more than 150% improvement in physician evaluation) in an independent, published, peer-reviewed clinical trial, and unlike minoxidil, the study reported no side effects.
