Text panel showing ‘Developed by Dr. James Kilgour, a Stanford-trained dermatologist’ with his portrait and founder quote
Infographic showing clinical trial results: 95% improved by week 6; 60.3% fewer hairs shed; 53% significant growth; 43-woman trial
Hand placing KilgourMD scalp serum into a travel case with testimonial from Olivia about gentleness and less shedding
Graphic showing Pure, Plant-based Ingredients with actives Anagain, Capixyl, Procapil labeled around Prevention Scalp Serum
Hand holding the black Treatment scalp serum next to the white Prevention serum on a blue tiled surface; overlay text We’re confident you’ll love your results
Instructional graphic showing 'How to Use': Step 1 fill dropper (press button, release to draw serum); Step 2 apply and massage onto scalp
The Science

The KilgourMD Dual Action System is backed by over 40 published clinical and laboratory studies – making it the most scientifically-validated natural formula on the market.

Clinical Results

The KilgourMD system combines Redensyl®, Capixyl®, and Procapil®—ingredients that have been evaluated in a published, peer-reviewed clinical trial reporting improvements across multiple hair-related outcomes, including physician assessments. In our 2026 trial, the serums were well tolerated, with no adverse effects reported.

How to Use
  1. Start with a clean scalp
    Apply to a dry or lightly damp scalp. These formulas are designed to absorb into the scalp, not coat the hair.
  2. One dropper daily
    Use one full dropper (about 1 mL) per day. If the dropper fills halfway, use a second to reach 1 mL. Consistency matters most. Apply all at once or split between morning and evening.
  3. Apply, massage, and leave in
    Part the hair and apply directly to thinning or shedding areas. Massage gently for 30–60 seconds. Do not rinse. Let it absorb and style as usual.
  4. Stay consistent
    Use daily. If you miss a day, simply resume—no need to double up.

View full application guide

Scalp Serum For Hair Growth - Best Serum For Hair Loss - KilgourMD

  • Decrease visible hair fall DECREASE VISIBLE
    HAIR FALL
  • Reverse lost fullness REVERSE LOST
    FULLNESS
  • Prevent premature scalp aging PREVENT
    PREMATURE SCALP
    AGING
Woman smiling and looking into a tabletop mirror in a bright, calm bathroom
KEY INGREDIENTS
What goes into The Prevention Serum

Capixyl® | strengthen + calm

A scientifically advanced complex that reduces scalp inflammation by 48% while increasing hair density by 79% in just four months. This powerful ingredient combines red clover extract rich in Biochanin A (a natural DHT suppressor) with acetyl tetrapeptide-3, a biomimetic peptide that strengthens hair anchoring at the root. By addressing both scalp inflammation and follicle miniaturization simultaneously, Capixyl® creates an optimal scalp environment where hair can thrive. Clinical studies show it outperforms the leading alternative by 81% while being drug and side-effect free.

Procapil® | nourish + strengthen

A bioengineered complex that improves scalp nutrient delivery by 121% while reducing hair loss by 58%. This trio of active molecules (biotinyl tripeptide-1, apigenin, and oleanolic acid) works synergistically to prevent premature follicle aging and strengthen the hair bulb structure, protecting against free radical damage while supporting cellular metabolism. It also suppresses DHT locally at the follicle without affecting hormone levels elsewhere, making it ideal for menopausal women seeking natural and safe solutions.

Anagain® | reactivate + extend

Derived from organic pea sprouts, this ingredient extends your hair's anagen (growth) phase by up to 78%, meaning each strand grows significantly longer before naturally shedding. By reducing the telogen (resting) phase by 34%, it ensures more follicles stay actively producing hair at any given time. AnaGain™ works alongside specific genes (FGF7 and Noggin) that control hair growth cycles. Scientific studies show it increases hair density through messaging to dermal papilla cells - the "command center" of each follicle responsible for hair production.

RootBioTec® | protect + stimulate

Revolutionary plant stem cell technology from basil hairy roots that reduces hair loss by 31% in just two months. This sustainable ingredient impacts 5α reductase II (the enzyme that creates DHT) while simultaneously locally stimulating dermal papilla cells to keep follicles in their growth phase longer. The patented "hairy root" extraction method preserves the full spectrum of bioactive compounds, including powerful antioxidants that protect follicles from environmental damage and premature aging. Clinical studies confirm it successfully prevents hair loss while promoting fuller, denser hair growth.

L Ascorbic Acid | shield + protect

By mitigating oxidative stress and promoting collagen gene expression, vitamin C combats photoaging and natural scalp aging. Clinical evidence supports its role in increasing dermal collagen, which is essential for maintaining healthy hair follicles. The vitamin C in our formula works synergistically with other antioxidants to protect follicles from free radical damage while supporting the structural integrity of the scalp tissue where follicles are anchored.

KilgourMD Soothing Shield | calm + soothe

Contained within The Prevention, piroctone, bisabolol, panthenol, and zinc combine to soothe the scalp and reduce harmful 'inflammaging'.

  • 0 %

    Saw results by week 6

    (clinical trial comprised of 43 women ages 30-65)

  • 0 %

    Fewer hairs shed in Combing Test

    (Day 120 vs. baseline)

  • 0 %

    Showed clinically significant growth

    (Day 120, expert assessment)

THE PROCESS
How to Grow

We intentionally designed our serums to work perfectly together, as well as with your lifestyle. For optimal results though, here are some tips from us.

Close-up of hand applying hair serum with dropper to a parted scalp
STEP 01
Start with a clean scalp

Apply to a dry or lightly damp scalp. These formulas are designed to absorb into the scalp, not coat the hair.

Hand holding two Kilgour md scalp serum bottles showing Prevention and Treatment labels against a light blue background
STEP 02
One dropper daily

Use one full dropper (about 1 mL) of each serum per day. If the dropper fills halfway, use a second to reach 1mL. Consistency matters most. Apply all at once or split between morning and evening.

Person parting scalp with fingers to apply hair serum, close up on thinning hair
STEP 03
Apply, massage, and leave in

Part the hair and apply directly to thinning or shedding areas. Massage gently for 30-60 seconds. Do not rinse. Let it absorb and style as usual.

Close-up of hand applying hair serum with dropper to a parted scalp
STEP 04
Stay consistent

Use daily. If you miss a day, simply resume, no need to double up.

FREQUENTLY ASKED QUESTION
Have a question? We are here to help.

What's the optimal way to use the Prevention serum?

The most important factor in seeing results from the serum is consistent, daily use. The optimal routine is whichever approach fits most naturally into your day and allows you to use it consistently — whether you apply morning or evening, or whether you apply on wet or dry hair or before styling.

The key is giving the product enough time to absorb properly. In our clinical studies, we allowed the products to absorb for approximately 12 hours, so we recommend avoiding showering or washing the treated area during that time.

My dropper only dispenses half a serum's worth.  How much should I actually be using?

The ideal dose is a full dropper which is approximately 1 mL. If the dropper does not fill all the way, repeat to make a full dropper. 

If your current dropper is difficult to measure, you can also use a different applicator, such as a generic minoxidil applicator purchased online, as long as it allows you to accurately measure 1 mL.

Your ideal amount may vary slightly depending on your hair density. Finer hair may require less product, while thicker hair may require more to adequately cover the scalp

What is the difference between the Prevention and Treatment serums?

The Treatment and Prevention serums were formulated by Dr. Kilgour to work together as a dual-action system. Because they target different aspects of the hair-thinning process, using both consistently is expected to provide the strongest overall results.

  • Prevention Serum: Focuses on creating a healthier scalp environment by supporting scalp balance, reducing inflammation and oxidative stress, and helping minimize shedding.
  • Treatment Serum: Focuses more on supporting follicle activity and improving the appearance of hair density and fullness in areas that are already thinning.

For the most comprehensive approach, we recommend using both serums together rather than relying on just one. Shop the bundle here.

What's the best technique for applying serum to get full scalp coverage if I have super fine or thick hair?

The recommended amount for each serum is 1 mL per day. However, depending on your hair type and density, you may need slightly more to ensure the serum reaches and covers your entire scalp.

For fine or thin hair, 1 mL may be enough to provide full scalp coverage. With thicker or denser hair, more hair sits between the serum and your scalp, so you may need to use additional product to make sure it reaches the areas you’re targeting.

For the best coverage, part your hair into sections and apply the serum directly to the scalp, rather than applying it primarily to the hair. This helps ensure the product reaches the scalp where it’s intended to work.

Is the prevention serum suitable for platinum blonde or predominantly grey hair?

For very light blonde or predominantly grey hair, the L-ascorbic acid in The Prevention may cause temporary warmth or brassiness at the roots if buildup occurs. This is purely cosmetic and fades after a few washes.

To minimize this, we recommend daily rinsing or using KilgourMD Shampoo to prevent buildup. If that’s not practical, consider using The Treatment Scalp Serum on its own instead of the full bundle.

How is KilgourMD different from regular hair growth products? Is it worth it?

KilgourMD stands out from other brands by formulating with clinically studied ingredients like Redensyl®, Capixyl®, and Procapil® at their proven effective dosages and in higher concentrations of active ingredients overall — while many other brands include only trace amounts for label appeal rather than real results.

What is your return policy?

While visual improvements typically take 3–6 months of consistent use, many people feel less scalp irritation and a healthier-feeling scalp within the first weeks of use!

We’re so  confident you’ll love your results, we offer a 90-day, no-questions-asked refund, backed by our full refund policy.

Refunds are subject to our full refund policy.

TESTIMONIALS

Hear what the people have to say

4.5
Rated 4.5 out of 5 stars
Based on 19 reviews
89%would recommend this product
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Customers Talked About
19 reviews
  • C
    Christi
    Flag of United States
    3 months ago
    Rated 5 out of 5 stars
    BELIEVE

    I was a skeptic but I ordered the three months to start, after one month I received an email asking if I’d noticed a reduction in hair loss, I said a discouraged “no”. I had three months so I kept using and began to notice a thickening of my hair and less hair loss. I was so excited that I ordered the shampoo and conditioner too! Now, after, I think, five months, I am a new old lady 🤣. Thick healthy hair! Thank you Kilgour! For all of you out there, this is not an overnight fix! Give it time and allow for small improvements over time. This product is so worth the wait and results !

  • M
    Michelle
    Flag of United States
    5 months ago
    Rated 5 out of 5 stars
    Was a skeptic, now a believer

    I noticed decreased shedding within a couple weeks. At 3-4 months noticed part seemed thicker. At 8 months I can say definitively I have regrown hair and do not feel self conscious about it any more. I am dealing with both perimenopausal and glp-1 hair loss.

  • A
    Alex
    Flag of United States
    Verified Buyer
    5 months ago
    Rated 4 out of 5 stars
    Dropper needs improvement.

    Just started using this a month ago. Am on my second bottle. The dropper/dispenser is terrible. You essentially get all or nothing when you push on it making it hard to put the serum in the areas you want. Thought it a bad dropper at first but the second bottle is the same. Wish the dropper was rubber so that you had more control over how much was dispensed. Otherwise it is too soon to tell if this is working for me yet or not.

  • L
    Linda
    Flag of United States
    5 months ago
    Rated 2 out of 5 stars
    Droppers don't fill, turns hair orange

    CONS: Droppers fill less than 1/2 way. If add more droppers to hair, may run out before end of month. Turns dyed blonde hair orange wherever it touches. I am starting my 3rd month, no results yet. I am going to try just using the Prevention Serum only occasionally on month 3 to try to get rid of the orange color on the top and temples of my hair. Hopefully, I can get it to again match the sides, back, and ends of my hair. FYI - purple shampoo and conditioner only help minimally. PROS: Smell is ok and does not leave hair sticky.

  • S
    Sarah
    Flag of United States
    6 months ago
    Rated 1 out of 5 stars
    The fragrance is overpowering

    If you are sensitive to synthetic fragrances, RUN.

    It is absolutely overpowering. I am prone to migraines and I will not be able to use this product. I am terribly disappointed; I checked the reviews first and the only one I could find that mentioned fragrance claimed this *wasn't* scented.

    Even if I weren't sensitive to synthetic fragrances, this is not a scent I would voluntarily choose.

    If they ever offer a fragrance-free formuulation, I'd be happy to try again. For now, I'll leave this to all of you who can tolerate SUPER heavy scents.