The Prevention Scalp Serum

The Prevention Scalp Serum

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The Science Behind
The KilgourMD Dual Action System is backed by over 40 published clinical and laboratory studies - making it the most scientifically-validated natural formula on the market.
Clinical Results
The combination of Redensyl®, Capixyl® & Procapil® (all found within the revolutionary KilgourMD system) was demonstrated to be superior to maximum strength 5% minoxidil across all outcome measures (including a more than 150% improvement in physician evaluation) in an independent, published, peer-reviewed clinical trial, and unlike minoxidil, the study reported no side effects.
How to Use
Apply one to two dropperfuls of The Prevention serum directly to your scalp and massage in once daily, ideally in the morning or at night before bed as the last step in your skincare routine. If showering, apply after towel-drying and do not rinse off.

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The Prevention Scalp Serum

The Prevention Scalp Serum

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    STRENGTHENS FOLLICLES
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    MAINTAIN THICK HAIR
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    PREVENTS 
SCALP AGING
Stop the signs of hair thinning before they begin! As your first defense, The Prevention Scalp Serum nourishes your follicles, to maintain thick, full-looking hair. Like an environmental and aging-related stress repellent for your scalp, it blocks aging forces that trigger visible hair thinning. Think of this step like an anti-aging serum for the scalp.  
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Key Ingredients
What goes into The Prevention Serum

Capixyl® | strengthen + calm

A scientifically advanced complex that reduces inflammation by 48% while increasing hair density by 79% in just 4 months. This powerful ingredient combines red clover extract rich in Biochanin A (a natural DHT blocker) with acetyl tetrapeptide-3, a biomimetic peptide that strengthens hair anchoring at the root. By addressing both inflammation and follicle miniaturization simultaneously, Capixyl® creates an optimal scalp environment where hair can thrive. Clinical studies show it outperforms minoxidil by 81% while being completely natural and side-effect free.

Procapil® | nourish + strengthen

A bioengineered complex that improves follicle blood flow by 121% while reducing hair loss by 58%. This trio of active molecules (biotinyl tripeptide-1, apigenin, and oleanolic acid) works synergistically to prevent follicle aging and strengthen the hair bulb structure. Procapil® fights follicle aging by protecting against free radical damage while improving cellular metabolism. It also blocks DHT locally at the follicle without affecting hormone levels elsewhere, making it ideal for menopausal women seeking natural solutions.

Anagain® | reactivate + extend

Derived from organic pea sprouts, this ingredient extends your hair's anagen (growth) phase by up to 78%, meaning each strand grows significantly longer before naturally shedding. By reducing the telogen (resting) phase by 34%, it ensures more follicles stay actively producing hair at any given time. AnaGain™ works by reactivating specific genes (FGF7 and Noggin) that control hair growth cycles. Clinical studies show it increases hair density through direct stimulation of dermal papilla cells - the "command center" of each follicle responsible for hair production.

RootBioTec® | protect + stimulate

Revolutionary plant stem cell technology from basil hairy roots that reduces hair loss by 31% in just 2 months. This sustainable ingredient blocks 5α reductase II (the enzyme that creates DHT) while simultaneously stimulating dermal papilla cells to keep follicles in their growth phase longer. The patented "hairy root" extraction method preserves the full spectrum of bioactive compounds, including powerful antioxidants that protect follicles from environmental damage and premature aging. Studies confirm it successfully prevents hair loss while promoting fuller, denser hair growth.

L-Ascorbic Acid | shield + protect

By mitigating oxidative stress and promoting collagen gene expression, vitamin C combats photoaging and natural scalp aging. Clinical evidence supports its role in increasing dermal collagen, which is essential for maintaining healthy hair follicles. The vitamin C in our formula works synergistically with other antioxidants to protect follicles from free radical damage while supporting the structural integrity of the scalp tissue where follicles are anchored.

KilgourMD Soothing Shield | calm + soothe

Contained within The Prevention, piroctone, bisabolol, panthenol, and zinc combine to soothe the scalp and reduce harmful 'inflammaging'.

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    RCP showed 2.54x better recovery rate (64.7%)

    compared to minoxidil (25.5%)*

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    RCP (88.9%) showed 1.5x greater visual improvement

    compared to minoxidil (60%)*

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    Received backing by over
    600 specialist doctors

THE PROCESS
How to Grow

We intentionally designed our serums to work perfectly together, as well as with your lifestyle. For optimal results though, here are some tips from us.

STEP 01
Apply once daily

Morning or evening - after towel-drying post-shower or on a dry scalp. Our serums are leave-on, so let them work all day (or night).

STEP 02
Prevention, then Treatment

No waiting needed between steps. Apply separately - don’t mix into one solution.

STEP 03
Massage in

Dispense 1-2 dropperfuls into your palm or directly onto the scalp. Using fingertips, focus on roots and thinning areas, not hair lengths.

STEP 04
Style as usual

Light, non-greasy, and invisible - won’t weigh down hair, affect colour, or stain fabrics.

FREQUENTLY ASKED QUESTION
Have a question? We are here to help.

Why subscribe rather than one off purchase?

During menopause, your scalp ages up to 10× faster than your facial skin. By age 50, your scalp can biologically resemble that of a 90-year-old. This accelerated aging is why many women lose nearly half their hair before they even notice the change. The good news? Breakthrough research shows that restoring a youthful scalp environment can reactivate growth — helping you grow fuller, healthier hair again, no matter your genetics or past treatment failures.

Isn’t it just genetics?

Genetics can make your hair more sensitive to thinning. However, genetics alone don’t seal your fate. Factors like hormonal changes during menopause, post-partum, stress, and oxidative damage all drastically intensify hair thinning - even in those without a strong genetic predisposition.
The KilgourMD Dual-Action System is designed to address these triggers, reducing the visible effects of 5-α reductase, calming inflammation, and supporting scalp health while rejuvenating growth.

As clinical studies on our active ingredients show, even if genetics aren't on your side, you can take control and promote thicker, healthier-looking hair.

How is KilgourMD different from regular hair growth products? Is it worth it?

Dr. James Kilgour, the Stanford dermatologist who created KilgourMD, revealed the truth: most hair products use only 1-2 active ingredients at minimum concentrations - the rest is filler and fragrance. They "look good on the label" but don't deliver results.

Here's what changes everything: During menopause, your scalp ages 10 times faster than your face. By 50, you could have an 80-year-old scalp. Regular treatments like minoxidil only mask symptoms while this "aged scalp" continues destroying follicles. That's why conventional treatments fail for menopausal women.

KilgourMD contains more than 15 clinical-strength actives with unique liposomal delivery that penetrates deep into the scalp. The results? 214% increase in hair growth, over 10,200 new hairs in 90 days (better than one transplant), and 81% more effective than minoxidil - without the side effects (based on results of in vitro and clinical studies).

Consider the math: Hair transplants cost $8,000-$25,000. Many women waste $200-300 monthly on volumizing shampoos, biotin gummies, and treatments that don't work. At $150 (or $127 with subscription), KilgourMD costs less than a cup of coffee a day.

KilgourMD addresses root causes for lasting results. With endorsement from more than 700 U.S. clinicians and a 30-day money-back guarantee on empty bottles, the real cost is continuing to use products that only treat symptoms while your scalp keeps aging.

Does it work for all hair types?

Absolutely! The Kilgour MD Dual-Action system works through principal, cellular-level mechanisms to address hair thinning areas that are universal across all hair types and textures.

Whether you have straight, wavy, curly, or coily hair, the underlying menopausal hair thinning is driven by the same biological processes.

Our clinically studied & scientifically formulated approach targets the sources of menopausal disruption areas, making it effective regardless of your specific hair type or texture.

Why is liposomal delivery important?

Liposomal delivery is like giving the active ingredients a special license that lets them pass directly into your scalp cells… These tiny phospholipid bubbles, which our ingredients are wrapped in, are made of the same material as your cell membranes, so your skin naturally welcomes them in.

This means ingredients can:

  • Bypass surface barriers
  • Penetrate deeper into scalp tissue
  • Deliver nutrients exactly where they're needed
  • Work more effectively than traditional topical treatments

By speaking the same "cellular language" as your skin, our liposomal technology ensures that our ingredients reach their target precisely where they can make the most difference, without adverse reactions.

How long does one bottle of each serum last?

Each of our serums is 30ml, which should last one month with generous usage, but up to 3 months if used in a more targeted way.

What is the 30-day guarantee?

We know that you will love our products as much as we do, especially when you see the results. While we recommend 3-6 months of consistent use to see optimal results, within the first 30 days signs of initial progress include a noticeable reduction in hair sheddin, reduced scalp inflammation, and the scalp feels healthier overall. Because we believe in our science,, we offer a 30-day no-questions refund on all of our products. Refunds are subject to our full refund policy.

TESTIMONIALS

Hear what the people have to say

Customer Reviews

Based on 92 reviews
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Ryan D.
Lightweight & Easy to Use

Was looking for something to help with my early-stage hair thinning, and this serum is now part of my daily routine. Feels like nothing on my scalp (which is great), and I’ve already noticed less hair in the drain when I shower. No complaints!

J
Jessica L.
Finally, A Scalp Serum That Works!

I've tried everything for my thinning hair—biotin, rosemary oil, even minoxidil (which made my scalp so itchy I had to stop). KilgourMD’s Prevention Scalp Serum is the first thing that has actually made a difference without irritation. My hair looks fuller, and I swear my shedding has decreased. Love that it’s fragrance-free too. I’m on my second bottle and will absolutely keep using it!

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Daniel R.
Feels Like a Luxury Treatment

This serum is lightweight, non-greasy, and absorbs fast. I use it before bed, and my scalp feels so much healthier. I’ve noticed less shedding in the shower and even some new baby hairs coming in around my hairline. It’s pricey, but considering the quality and results, worth every penny.

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Megan S.
Not Sure Yet, But Hopeful

I’ve been using this for about three weeks now. It absorbs nicely and doesn’t leave my scalp feeling greasy. I haven’t noticed any dramatic changes yet, but I’m sticking with it because my scalp definitely feels healthier and less dry. Hoping for some real hair growth in the coming months!

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Travis G.
Worth Every Dime

I never leave reviews, but this stuff deserves it. My hairline was receding, and I was desperate to find something before jumping to prescription treatments. Two months in, and I can see baby hairs filling in! It’s slow, but it’s real. Can’t recommend this enough.

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Natalie P.
Helps With My Dry, Itchy Scalp Too!

Wasn’t expecting this serum to help with my scalp issues, but it totally has. I used to get super dry and flaky around my hairline, and since using this, my scalp feels so much more balanced. It’s also helping my hair look fuller! No strong smell, no irritation—just a really well-made product.

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Adam M.
Pretty Impressed So Far

Okay, so I was skeptical about any hair product actually making a difference, but after using this for a couple of months, I do think my hair looks thicker. The application is easy, and it doesn’t leave my hair greasy like other serums I’ve tried. Giving it 4 stars just because I want to see more long-term results before I call it a miracle product.

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Olivia H.
My Dermatologist Recommended This!

I have super sensitive skin, so I was nervous to try anything on my scalp, but my dermatologist actually recommended this serum. It’s so gentle but effective. I’ve been using it for about six weeks, and my shedding has definitely decreased. My hair even looks shinier. Love that there’s no artificial fragrance—just a clean, science-backed formula.

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Brianna T.
It’s Actually Helping My Edges Grow Back!

My edges have been thinning from years of braids and tight ponytails. I started using this serum nightly, and after about 8 weeks, I can SEE the difference. Tiny little baby hairs are sprouting up! Super lightweight, non-sticky, and doesn’t weigh my hair down. I’m hooked.

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Sarah M.
The Best Investment in My Hair

Haircare is self-care, and this serum is proof of that! After two months, my hair feels stronger and thicker. My ponytail has more volume, and even my stylist noticed a difference! This is officially a staple in my routine.